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Updated DIRM Syllabus & Practicals

Course Topics Course Coordinator
Cell Biology
  • Cell and Organelle Structure and Function
  • Cell Cycle
  • Cell Signaling
  • Cell Metabolism
  • Cellular Aging
Developmental Biology
  • Mechanism of Development
  • Cell Type Determination, Organogenesis and Morphogenesis
  • The Blastocytes and Embryonic Stem Cells
  • Alternative Sources of Pluripotent Stem Cells
  • Mechanisms of Regeneration
Immunology
  • Anatomy of Immune System
  • Acute and Chronic Inflammation
  • Dendritic Cells and Vaccine
  • Host Defense Against Infections
  • Angiogenesis and Immune Regulation

Course Topics Course Coordinator
Molecular Biology
  • DNA Replication, Recombination, and Repair
  • Fundamentals of Gene Structure and Eukaryotic Transcription
  • Effect of Chromatin on Gene Regulation
  • Analysis of Transcriptional Networks
  • RNAi and Micro RNA Mechanisms
Physiology & Anatomy
  • Organization of Human Body & Cell Types
  • Skeletal System & Joints
  • The Muscular System
  • CNS & PNS
  • The Endocrine System
Cancer Biology & Infectious Disease
  • Origin & Overview of Cancer
  • Cancer Immunology
  • Cancer Systems Biology
  • Cancer Diagnostics & Treatments
  • Infectious Agents & Cancer

Course Topics Course Coordinator
Basics of Stem Cell Biology
  • Introduction to Concepts of Stem Cell Biology
  • Mesenchymal & Hematopoietic Stem Cells
  • Neural, Cardiac, Breast, Epithelial Stem Cells
  • Stem Cells & Cancer
  • Stem Cells in Regenerative Medicine
Stem Cell Technologies, Commercialization & Treatment
  • Working with Progenitor & Various Stem Cell Types
  • Ex-vivo Expansion of MSCs
  • Stem Cell Reprogramming
  • Stem Cell Banking
  • Stem Cell-Based Regenerative Medicine
Basics of Transplantations & Blood Transfusions
  • Basic Immunology of Transplantation
  • Immunosuppressive Therapy; GVHD
  • Bioethics of Transplantations
  • Blood Services & Alternate Transfusions
  • Blood Transfusion Management

Course Topics Course Coordinator
Hematology / Bone Marrow Transplantation
  • Autologous & Allogenic Transplantations
  • Bone Marrow Development & Function
  • Ethical Issues in BMT
  • Immunological Treatment Approaches
  • Donor Types & Choices
Umbilical Cord & Placenta
  • Cord Blood for Transplantation
  • Cord Blood Banking
  • Amniotic & Placental Stem Cells
  • Placenta & Fetus Structure & Function
  • Ethical Considerations
Basics of Clinical Research
  • Fundamentals of Clinical Trials
  • Principles & Practice of Clinical Research
  • Regulatory Affairs
  • Ethics in Clinical Research
  • Biostatistics & Data Analysis

Course Topics Course Coordinator
Regenerative Medicine
  • Overview of Organ Failure
  • Mechanisms of Cell Regeneration
  • Nuclear Reprogramming & Plasticity
  • Directed Differentiation of Stem Cells
  • Commercial & Clinical Applications

Course Topics Course Coordinator
Cell Therapies
  • Principles of Cell Therapies
  • Applications in Diabetes
  • Applications in Cancer
  • Applications in Cardiovascular Diseases
  • Applications in Wound Healing & Burn Injuries

Course Topics Course Coordinator
Basics of Stem Cell Transplantations
  • Types of Stem Cell Transplants
  • Transplantation Process & Post Management
  • Ex-vivo Expanded Stem Cell Transplants
  • Bioethics & Biosafety
  • Autophagy in Stem Cells

Week 1: Foundations of Regenerative Medicine in Gynaecology

  • Basics of stem cells, PRP, exosomes & growth factors
  • Mechanisms of regeneration & angiogenesis
  • Regulatory & ethical considerations

Week 2: Ovarian Regeneration & Infertility

  • Ovarian aging & insufficiency
  • PRP & stem cell-based ovarian rejuvenation
  • Evidence-based PRP protocols
  • Case studies

Week 3: Endometrial Regeneration

  • Thin endometrium & Asherman's syndrome
  • PRP & regenerative options
  • Implantation improvement strategies
  • Doppler assessment

Week 4: Urogynaecology & Vaginal Aesthetics

  • Regeneration for urinary incontinence
  • Vaginal laxity & aesthetics
  • Combination protocols (laser + PRP)
  • Medico-legal considerations

Assessment

  • MCQ Test
  • Case-based Discussion

Hands-On Clinical Training (15 Days)

Days 1–3: Ovarian Regeneration

  • Live PRP procedures
  • Patient counselling
  • Hands-on practice

Days 4–6: Endometrial Regeneration

  • Hysteroscopic PRP/Stem cell applications
  • Case discussions

Days 7–10: Urinary Incontinence

  • Diagnostics
  • PRP + RF/Laser techniques
  • Supervised training

Days 11–15: Vaginal Aesthetics

  • Non-surgical rejuvenation
  • PRP & fillers techniques
  • Documentation & medico-legal aspects
  • Final practical + viva